Betaine: The Major Weight Loss And Muscle Gain Supplement Nobody Knows About

bicepcurl2Have you eaten any beets lately? I can’t stand them, but research shows that a chemical named after them, betaine (pronounced beet’-uh-een) may be an effective way to gain muscle mass while simultaneously losing fat, making it one of the few chemicals to offer both of these desired diet benefits.

Betaine is also known as trimethylglycine (TMG). While I am not going to get too into the science of methyl donation, just know that as a “methyl donor”, betaine may have a variety of benefits, including improving mental function and having liver health benefits.

To order from Amazon: Betaine HCL or without the HCL: TMG/Betaine Annhydrous (this bulk powder is the best deal by far). 

A number of studies have concluded that betaine supplementation boosts strength and power (see, for example: Journal of the International Society of Sports Nutrition, July 2010) .

However, the most exciting research was performed recently at the College of Springfield in Massachusetts.

Researchers had a group of males weight-train for six weeks.One group took 1.25 grams of betaine twice a day, and the control group (also weight training) supplemented with a placebo. The researchers reported in a 2013 issue of the same journal I referenced above that the subjects taking betaine increased muscle mass by four pounds and arm size by ten percent (!), while decreasing body fat by seven percent. The placebo group experienced no increase in muscle mass/arm size and no body fat loss.

Also, another study found increased production of human growth hormone following workouts with 2.5 grams a day of betaine supplementation.

So, while the research is preliminary, supplementing with betaine/TMG may help you see quicker muscle gains and faster weight loss. Either way, other studies show a variety of athletic benefits for TMG. For example, a brand new study shows that betaine helps runners sprint faster.

Note that betaine comes in two forms. Betaine Hydrochloride (HCL) is betaine bound to HCL. The hypothesis is that the HCL in the formula improves digestion in the stomach by making it more acidic. Betaine HCL is 76% betaine, so if you see an amount on a bottle (such as 600 mg betaine HCL), just multiply that amount by .76 to get the actual betaine content (600 mg of betaine HCL contains 456 mg betaine). Betaine anhydrous is often labeled as TMG or Trimethlyglycine. Both are cheap and readily available.

So giving this inexpensive supplement might be worth a try. If you don’t want to take supplements, quinoa and Spinach are particularly high in this nutrient.

About David Bennett

David Bennett is author of seven self-help books, and an in-demand speaker and consultant. Over a million readers per year read his online content, and his writings have been referenced in many publications and news outlets, including Girls Life, Fox News, the New York Times, Huffington Post, and BBC. He also writes for The Popular Teen, and other sites. Follow him on Twitter.


  1. […] few months ago I posted an article about Betaine and weight loss (and muscle gain). The small studies out there suggest betaine, aka trimethylglycine (TMG), can increase weight loss […]

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